I have a long-standing interest in DNA-repair-mediated resistance to alkylating agents and radiation in human brain tumors, and have directed a number of translationally relevant projects that investigate strategies to circumvent resistance. I have broad training and experience in DNA repair, radiobiology and DNA replication, and a long history of directing NIH- and foundation-funded grants key research areas for our proposal.
Dr. Silbergeld is the Arthur A. Ward Jr. professor of neurological surgery and is based at the UW Medical Center. He is also an adjunct professor of pathology. He specializes in tumors of the central nervous system, pituitary tumors, epilepsy surgery and radiosurgery with the Gamma Knife. He is board certified in neurological surgery.
His research program focuses on gliomas, a type of brain tumor, and on methods to break the blood/brain barrier to deliver chemotherapy to malignant brain tumors.