Caroline Hadley, MD

Job Title
Acting Instructor

Dr. Hadley was born and raised in Washington, DC. She graduated from Duke University with a Bachelor of Science in Biology in 2011. She completed medical school at Baylor College of Medicine, where she stayed for her neurosurgery residency. Her interests are skull base, open vascular neurosurgery, and neurocritical care.

Clinical Interest

Skull base surgery, Open vascular, neurocritical care

Research Interests

Genetic drivers of meningiomas, healthcare disparities/barriers to access to health care, neurocritical care


Bachelor of Science, Duke University, 2011

Doctor of Medicine, Baylor College of Medicine, 2016


Peer Reviewed Journal Articles

  1. Khan AB, English CW, Chen WC, Athykuri P, Bayley JC, Brandt VL, Shetty A, Hadley CC, et al. Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma. Acta Neuropathol. Published online February 2, 2023. doi:10.1007/s00401-023-02543-7 PMID 36729132
  2. Shahbandi A, Shah DS, Hadley CC, Patel AJ. The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review. Cancers (Basel). 2023;15(2):483. doi:10.3390/cancers15020483 PMID: 36672431
  3. Hadley C, Patel A. Commentary: The Association of Language Barriers With Process Outcomes After Craniotomy for Brain Tumor. Neurosurgery. 2022 Sep 7. doi: 10.1227/neu.0000000000002135. Epub ahead of print. PMID: 36069584.
  4. Karas PJ, Gopakumar S, Lazaro TT, Lee S, Khan AB, Hadley C, Patel A 3-Dimensional Modeling in Virtual Reality for Resection of a Pineal Region Falcotentorial Meningioma. World Neurosurg. 2022;161:110. doi:10.1016/j.wneu.2022.02.058 PMID: 35202874
  5. Bayley JC, Hadley CC, Harmanci AO, Harmanci AS, Klisch TJ, Patel AJ. Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies. Sci Adv. 2022;8(5):eabm6247. doi:10.1126/sciadv.abm6247 PMID: 35108039

6.      Jackson HN, Hadley CC, Khan AB, et al. Racial and Socioeconomic Disparities in Patients With Meningioma: A Retrospective Cohort Study. Neurosurgery. 2022;90(1):114-123. doi:10.1227/NEU.0000000000001751 PMID: 34982878

7.      Gadot R, Khan AB, Patel R, Goethe E, Shetty A, Hadley C et al. Predictors of postoperative seizure outcome in supratentorial meningioma. J Neurosurg. Published online December 10, 2021:1-10. doi:10.3171/2021.9.JNS211738 PMID: 35099915

8.      Mohanty A, Caldwell DJ, Hadley CC, Gibson A, Ravanpay A, Patel AJ. Virtual Interviews in Neurosurgery Resident Selection-A Work in Progress. World Neurosurg. 2021;155:e412-e417. doi:10.1016/j.wneu.2021.08.074 PMID: 34428584

9.      Hadley C, Burkhardt JK, Johnson JN, Kan P, Group ENR. Crossing the Carotid Siphon: Techniques to Facilitate Distal Access in Tortuous Anatomy: 2-Dimensional Operative Video. Operative Neurosurgery. Published online 2021. PMID: 33822191

10.  Gopakumar S, Srinivasan VM, Hadley CC, et al. Intracranial Solitary Fibrous Tumor of the Skull Base: 2 Cases and Systematic Review of the Literature. World Neurosurg. Published online February 17, 2021. doi:10.1016/j.wneu.2021.02.026 PMID: 33609763

11.  Srinivasan VM, Hadley CC, Patel AJ, et al. The history of neurosurgery at Baylor College of Medicine. J Neurosurg. Published online February 19, 2021:1-11. doi:10.3171/2020.7.JNS201196 PMID: 33607618

12.  Hadley C, North R, Srinivasan V, Kan P, Burkhardt JK. Elective Sonolucent Cranioplasty for Real-Time Ultrasound Monitoring of Flow and Patency of an Extra- to Intracranial Bypass. J Craniofac Surg. Published online March 6, 2020. doi:10.1097/SCS.0000000000006225 PMID: 32149973

13.  Hadley C, Srinivasan V, Burkhardt JK, et al. Forming the Simmons Catheter for Cerebral Angiography and Neurointerventions via the Transradial Approach-Techniques and Operative Videos. World Neurosurg. 2021;147:e351-e353. doi:10.1016/j.wneu.2020.12.054 PMID: 33346049

14.  Srinivasan VM, Hadley CC, Prablek M, et al. Feasibility and safety of transradial access for pediatric neurointerventions. J Neurointerv Surg. 2020;12(9):893-896. doi:10.1136/neurintsurg-2020-015835 PMID: 32241922

15.  Khan AB, Gadot R, Shetty A, Bayley J, Hadley C, et al. Identification of novel fusion transcripts in meningioma. J Neurooncol. 2020;149(2):219-230. doi:10.1007/s11060-020-03599-1 PMID: 32949309

16.  Khan AB, Goethe EA, Hadley CC, et al. Infundibular Epidermoid Cyst: Case Report and Systematic Review. World Neurosurg. Published online July 5, 2019. doi:10.1016/j.wneu.2019.06.205 PMID: 31284058

17.  Hadley C, Sheth S, Fargen KM, et al. Mechanical thrombectomy for acute stroke in patients with target and unrelated vessel AVMs and AVFs: A case series. World Neurosurg. Published online April 12, 2019. doi:10.1016/j.wneu.2019.04.019 PMID: 30986580

18.  Lee S, Karas PJ, Hadley CC, et al. The Role of Merlin/NF2 Loss in Meningioma Biology. Cancers (Basel). 2019;11(11). doi:10.3390/cancers11111633 PMID: 31652973

19.  Du RY, LoPresti MA, Hadley CC, Lam S. Systematic review of clinician awareness of mycotoxin impact in neural tube defects and best practices for pediatric neurosurgeons: implications for public health and policy. Childs Nerv Syst. 2019;35(4):637-644. doi:10.1007/s00381-018-4023-3 PMID: 30552445

20.  Lam S, Pan IW, Strickland BA, Hadley C, et al. Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience. J Neurosurg Pediatr. 2017;19(3):273-281. doi:10.3171/2016.9.PEDS16275 PMID: 28084921

21.  LoPresti M, Buchanan EP, Shah V, Hadley CM, Monson LA, Lam S. Complete Resolution of Papilledema in Syndromic Craniosynostosis with Posterior Cranial Vault Distraction. J Pediatr Neurosci. 2017;12(2):199-202. doi:10.4103/jpn.JPN  PMID: 28904587

22.  Lam S, Luerssen TG, Hadley C, et al. The health belief model and factors associated with adherence to treatment recommendations for positional plagiocephaly. J Neurosurg Pediatr. 2017;19(3):282-288. doi:10.3171/2016.9.PEDS16278 PMID: 28084919

23.  Zhang X, Hadley C, Jackson IL, et al. Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung. Free Radic Res. 2016;50(8):875-886. doi:10.1080/10715762.2016.1189078 PMID: 27367846

24.  Hadley C, Mohila CA, Luerssen TG, Lam S. Congenital neurocristic tumor presenting as an isolated calvarial defect in an infant: case report. J Neurosurg Pediatr. 2015;16(1):46-49. doi:10.3171/2014.12.PEDS14497 PMID: 25837885

25.  Hadley C, Lam SK, Briceño V, Luerssen TG, Jea A. Use of a formal assessment instrument for evaluation of resident operative skills in pediatric neurosurgery. J Neurosurg Pediatr. 2015;16(5):497-504. doi:10.3171/2015.1.PEDS14511 PMID: 26314202

26.  Sayama C, Hadley C, Monaco GN, et al. The efficacy of routine use of recombinant human bone morphogenetic protein-2 in occipitocervical and atlantoaxial fusions of the pediatric spine: a minimum of 12 months’ follow-up with computed tomography. J Neurosurg Pediatr. 2015;16(1):14-20. doi:10.3171/2015.2.PEDS14533 PMID: 25860982

27.  Sahni D, Prasad P, Hadley C, et al. Pediatric pedicle screw (In) accuracy based on postoperative computed tomography. Journal of Pediatric Neuroradiology. 2014;3(4):161-169.

28.  Hadley C, Gressot LV, Patel AJ, et al. Osteosarcoma of the cranial vault and skull base in pediatric patients. J Neurosurg Pediatr. 2014;13(4):380-387. doi:10.3171/2013.12.PEDS13359 PMID: 24483254

29.  Jackson IL, Xu PT, Nguyen G, et al. Characterization of the dose response relationship for lung injury following acute radiation exposure in three well-established murine strains: developing an interspecies bridge to link animal models with human lung. Health Phys. 2014;106(1):48-55. doi:10.1097/HP.0b013e3182a32ccf PMID: 24276549

30.  Jackson IL, Xu P, Hadley C, et al. A preclinical rodent model of radiation-induced lung injury for medical countermeasure screening in accordance with the FDA animal rule. Health Phys. 2012;103(4):463-473. doi:10.1097/HP.0b013e31826386ef PMID: 22929472

31.  Jackson IL, Zhang X, Hadley C, et al. Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung. Free Radic Biol Med. 2012;53(2):337-346. doi:10.1016/j.freeradbiomed.2012.04.014 PMID: 22588005

32.  McGurk R, Hadley C, Jackson IL, Vujaskovic Z. Development and dosimetry of a small animal lung irradiation platform. Health Phys. 2012;103(4):454-462. PMID: 23091878


Book Chapters

  1. Hadley CC, Srinivasan V, Kan P: Giant Fusiform Basilar Artery Aneurysms: Endovascular Management (Caroline C. Hadley, Visish M. Srinivasan and Peter Kan, Department of Neurosurgery, Baylor College of Medicine, Houston, TX, US), in Basilar Artery: A Clinical Review. NOVA SCIENCE, 2019
  2. Jackson IL, Rubin P, Hadley C, Vujaskovic Z. Molecular Mechanisms of Radiation Induced Injury. In: Rubin P, Constine LS, Marks LB, eds. ALERT - Adverse Late Effects of Cancer Treatment. Medical Radiology. Springer Berlin Heidelberg; 2014:41-51. doi:10.1007/978-3-540-72314-1_4


Presentations and Posters

  1. Hadley C, Shetty A, Klisch T, Patel A: Differences in Incidence of Meningioma Classes in Biological Sex and Ethnicity. North American Skull Base Society Annual Meeting, Tampa FL, USA, 2023.
  2. Hadley C, Bayley J, Harmanci A, Harmanci A, Klisch T, Patel A: Differential Extracellular Matrix Component Expression in Aggressively Recurrent Atypical Meningiomas. Annual Meeting of the American Association of Neurological Surgeons, Orlando, FL, USA, 2021.
  3. Hadley C, Lam SK, Briceño V, Luerssen TG, Jea A: Use of a formal assessment instrument for evaluation of resident operative skills in pediatric neurosurgery. Annual Meeting of the AANS CNS Section on Pediatric Neurological Surgery, Amelia Island, FL, USA, 2014.
  4. Bollo R, Hadley C, Gressot L, Patel A, Wang L, Flores R, Whitehead W, et al.: Osteosarcoma of the Cranial Vault and Skull Base in Children: Case Series and Literature Review. Annual Meeting of the AANS CNS Section on Pediatric Neurological Surgery, Toronto, ON, Canada, 2013.
  5. Hadley C, Zhang X, Vujaskovic Z. AEOL10150, a potent catalytic antioxidant, does not protect non-small cell lung cancer xenografts against radiation-induced cytotoxicity. International Congress of Radiation Research, Warsaw, Poland, 2011.