Congratulations to Dr. Andrew Ko who was awarded a Kuni Foundation research grant in the amount of $75,000 for his project “Measurement and Modulation of Neural Activity in Brain Cancer.” Dr. Ko plans to adapt electrophysiological techniques from current research in fields such as epilepsy to study the glioma-infiltrated brain in vivo. Dr. Ko will apply neuromodulation, a stimulation technique to vary cortical excitability, to patients undergoing surgery for brain cancer. He will measure and then modulate electrical activity in the glioma-infiltrated brain before resection of tumor tissue. Resected tissue will be examined at the single-cell level to identify changes induced by neuromodulation. Dr. Ko expects to see that neuromodulation can induce changes that indicate cells are less excitable, and less likely to contribute to tumor growth. Examining these changes in detail may provide valuable insight into the development of drugs to treat brain cancer, or potentially ways to use electrical stimulation to slow the growth of gliomas.
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