Each year, NINDS highlights a selection of research advances that reflect the breadth, rigor, and impact of the science they support. This year, NINDS recognized the multi-center clinical trial led by UW Medicine including the department’s own Michael A. Williams, MD, and Rehab Medicine’s Nickolas Dasher, PhD. Rob Bonow, MD is a site collaborator.
Idiopathic normal-pressure hydrocephalus (iNPH) is an often-misdiagnosed condition that causes problems with walking, thinking, and bladder control. Until now, few treatment options have been verified by clinical research. This randomized clinical trial tests the effects of shunt surgery in people with iNPH. In this procedure, a surgeon implants a small tube into the brain to drain extra fluid that is causing symptoms. The study provides important evidence to guide diagnosis and treatment decisions for managing a condition that is often underrecognized.