Dominic Siler, MD, PhD

Dominic Siler Headshot
Job Title
Acting Instructor
Biography

Dominic Siler grew up in the Pacific Northwest and moved to southern California to attend California State University Long Beach as a music performance major. While there, he discovered a passion for medicine and neuroscience, then changed directions to pursue a career as a physician-scientist. He returned to Portland, Oregon to attend OHSU as part of the MSTP MD, PhD program. During his training, he successfully competed for NIH F30 funding and obtained a PhD in the laboratory of Nabil Alkayed MD, PhD, studying mechanisms of delayed cerebral ischemia following subarachnoid hemorrhage. His dissertation now serves as the groundwork for a novel therapy to treat patients with subarachnoid hemorrhage and is currently in phase 1 clinical trials. After graduation, Dominic stayed on to train with OHSU’s neurosurgery program. While in training, his clinical practice and research focused on the critically ill neurosurgery population, especially neurotrauma. He is now completing a neurotrauma/neurocritical care fellowship at the University of Washington. Outside of neurosurgery, Dominic spends all of his free time with his wife, Janelle, and two kids, Bastian and Esme, who are the light of his life.

Clinical Interest

Traumatic Brain injury, Spinal Cord injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Hydrocephalus, Syringomyelia, Neurocritical Care.

 

Research Interests

Soluble Epoxide Hydrolase in neurocritical illness, cerebrospinal fluid dynamics, novel treatments for hydrocephalus, simulation in healthcare and education.

 

Education

2024-2025 Neurotrauma Fellowship, University of Washington

2017-2024 Neurosurgery Residency, Oregon health & Science University

2016-2017 Neuro-Oncology Fellowship, Oregon health & Science University

2007-2016 MD, PhD, Oregon Health & Science University

2006-2007 NIH Post-Baccalaureate Research Fellowship, Baltimore, MD

2000-2006 BS Biology, California State University, Long Beach