Christine was born in South Korea but moved to Reno, NV when she was 8 years old. She attended Dartmouth College where she majored in chemistry. She graduated with high honors and completed her thesis on organic synthesis research which focused on developing synthesis pathways to make optically active monomers to construct chiral and conformationally rigid synthetic oligomers that have potential therapeutic properties. Before matriculating into medical school, she worked as a sushi chef in Las Vegas and as a team host at the 2018 PyeongChang Winter Olympics. She then attended Duke University for medical school during which she received her Master of Engineering in artificial intelligence from Duke Pratt School of Engineering. In medical school, she primarily focused on research studying interneuron transplantation into human and mouse epileptic tissue as a novel therapy for epilepsy and applying machine learning (computer vision, natural language processing) and predictive modeling for patient outcomes. She served as the president of the Neurosurgery Interest Group, founder of Women in Neurosurgery, and president of Data Club through which she hosted various campus-wide events such as the Data Competition, AI Start-Up Competition, and the Duke Digital Venture Challenge. In her free time, Christine enjoys hosting sushi nights, translating books, hiking, running, golfing, playing tennis and piano, and building/designing nanoblocks.
Spine
Brain and spine trauma
Patient outcomes, imaging biomarkers of intervertebral disc metabolism, machine learning, artificial intelligence, robotics, device development
Duke University School of Medicine, MD, 2023
Duke Pratt School of Engineering, MEng (Artificial Intelligence), 2022
Dartmouth College, BA (Chemistry), 2017
Barr and Spach Medicine and Engineering Fellowship
Duke Institute for Health Innovation Clinical Research and Innovation Scholarship
GradEngage Community Engagement Fellowship
AAN Medical Student Research Scholarship
AΩA Carolyn L. Kuckein Student Research Fellowship
NREF Medical Student Summer Research Fellowship
John L. Zabriskie Jr. Research Fellowship
American Institute of Chemists Student Award
Paul R. Shafer & Douglas M. Bowen Award
Chandler T. White 1916 Research Prize
1. Qian Y, Li J, Zhao S, Matthews E, Adoff M, Zhong W, An X, Yeo M, Park C, Wang BS, Southwell DG, Huang J. Programmable RNA Sensing for Cell Monitoring and Manipulation. Nature. https://doi.org/10.1038/s41586-022-05280-1.
2. Feng W, Domeracki A, Park C, Shah S, Chhatbar P, Pawar S, Chang C, Hsu PC, Hasan D, Sokhadze E, Zhang Q, Liu H. Revisiting Transcranial Light Stimulation as a Stroke Therapeutic—Hurdles and Opportunities. Transl Stroke Res. doi: 10.1007/s12975-022-01103-7
3. Park C, Mummaneni PV, Gottfried ON, Shaffrey CI, Than KD, Tang AJ, Bisson EF, Sherrod BA, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Agarwal N, Chou D, Haid RW, Bydon M, Chan AK. Which supervised machine learning algorithm can best predict achievement of minimum clinically important difference in neck pain after surgery in patients with cervical myelopathy? A QOD study. Neurosurg Focus.
4. Vargas E, Shabani S, Mummaneni PV, Park C, Rechav Ben-Natan A, Rivera J, Huang J, Berven S, Braunstein S, Chou D. In the Absence of Cord Compression, Does Surgery for Metastatic Spinal Tumors Improve Functional Outcomes in Potentially Unstable Spines (SINS 7-12)? J Neurosurg Spine.
5. Park C, Shaffrey CI, Than KD, Michalopoulos G, El Sammak S, Chan AK, Shaffrey CI, Than KD, Tang AJ, Bisson EF, Sherrod BA, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Agarwal N, Chou D, Haid RW, Bydon M, Mummaneni PV, Gottfried ON. What factors influence surgical decision making in anterior versus posterior surgery for cervical myelopathy? A QOD analysis. J Neurosurgery Spine.
6. Park C, Shaffrey CI, Than KD, Chan AK, Shaffrey CI, Than KD, Bisson EF, Sherrod BA, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Agarwal N, Chan AK, Chou D, Haid RW, Bydon M, Mummaneni PV, Gottfried ON. Does the number of social risk factors affect long-term patient-reported outcomes and satisfaction in those with cervical myelopathy? A QOD study. J Neurosurgery Spine.
7. Chan AK, Park C, Shaffrey CI, Gottfried ON, Than KD, Bisson EF, Bydon M, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Alvi MA, Sherrod BA, Agarwal N, Chou D, Glassman SD, Haid RW, Mummaneni PV. What Factors Predict the Best Outcomes for Disability, Quality of Life, and Functional Status Following Surgery for Cervical Spondylotic Myelopathy? J Neurosurgery Spine.
8. Chan AK, Park C, Shaffrey CI, Gottfried ON, Than KD, Bisson EF, Bydon M, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Alvi MA, Sherrod BA, Agarwal N, Chou D, Glassman SD, Haid RW, Mummaneni PV. Comparing Those Most Satisfied Versus Least Satisfied Following Surgery for Cervical Spondylotic Myelopathy: Are There Differences in Baseline Characteristics? J Neurosurgery Spine.
9. Chan AK, Bydon M, Bisson EF, Glasman SD, Foley KT, Shaffrey CI, Potts EA, Shaffrey ME, Coric D, Knightly JJ, Park P, Wang MY, Fu KM, Slotkin JR, Asher AL, Virk MS, Michaelpoulos G, Guan J, Haid RW, Agarwal N, Park C, Chou D, Mummaneni PV. Minimally invasive versus open transforaminal lumbar interbody fusion for grade 1 lumbar spondylolisthesis: 5-year follow-up from the QOD multi-center prospective registry. Neurosurg Focus. 2022. doi: 10.3171/2022.10.FOCUS22602
10. Chan AK, Shaffrey CI, Park C, Gottfried ON, Than KD, Bisson EF, Bydon M, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Alvi MA, Sherrod BA, Agarwal N, Chou D, Glassman SD, Haid RW, Mummaneni PV. Does Self-Reported Depression and Anxiety Influence Outcomes Following Surgery for Cervical Spondylotic Myelopathy? J Neurosurg Spine.
11. Kelly-Hedrick M, Abd-El-Barr M, Aarabi B, Curt A, Howley SP, Harrop JS, Kirshblum S, Neal CJ, Noonan VK, Park C, Ugiliweneza B, Tator C, Toups EG, Fehlings MG, Williamson T, Guest J. The Importance of Prospective Registries and Clinical Research Networks in the Evolution of Spinal Cord Injury Care. J Neurotrauma. 2022. doi: 10.1089/neu.2022.0450
12. Ambati VS, Morshed R, Park C, Salha DM, Chryssikos T, Mummaneni PV. Technical Nuances of Cervical Laminoplasty: Operative Video. Clin Spine Surgery.
13. Xia M, Kheterpal MK, Wong SC, Park C, Ratliff W, Carin L, Henao R. Lesion identification and malignancy prediction from clinical dermatological images. Sci Rep. https://doi.org/10.1038/s41598-022-20168-w.
14. Cook CE, George SZ, Lentz T, Park C, Shaffrey CI, Goodwin CR, Than KD, Gottfried ON. High impact chronic pain transition in lumbar surgery recipients. Pain Medicine. doi: 10.1093/pm/pnac150.
15. Jeong HK, Park C, Henao R. Kheterpal M. Deep learning in dermatology: a systematic review of current approaches, outcomes and limitations. J Invest Dermatol. https://doi.org/10.1016/j.xjidi.2022.100150.
16. Massengale KEC, Jones MA, Liao J, Park C, Old M. Priority areas for child diaper access: low-income neighborhoods with limited retail access to the basic need of diapers. Health Equity. https://doi.org/10.1089/heq.2021.0192.
17. Chan AK, Shaffrey CI, Gottfried ON, Park C, Than KD, Bisson EF, Bydon M, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialan LM, Turner J, Michaelopoulos G, Sherrod BA, Agarwal N, Chou D, Glassman SD, Haid RW, Mummaneni PV. Cervical spondylotic myelopathy with severe axial neck pain: Is anterior or posterior approach better? J Neurosurg Spine. https://doi.org/10.3171/2022.6.SPINE22110
18. Park C, Sinha SR, Southwell DG. Laser ablative treatment of musicogenic epilepsy arising from dominant mesial temporal lobe. J Neurosurg Case Lessons. 2022. doi: 10.3171/CASE2295
19. Park C, Buckley ED, Van Swearingen AED, Giles W, Herndon JE, Kirkpatrick JP, Anders CK, Floyd SR. Systemic therapy type and timing effects on radiation necrosis risk in HER2+ breast cancer brain metastases patients treated with stereotactic radiosurgery. Front Oncol. 2022. doi: 10.3389/fonc.2022.854364
20. Park C, Jeong HK, Henao R, Kheterpal M. Applicability of Facial De-Identification Methods for Privacy Protection in Dermatology: Systematic Review. JMIR Dermatology. 2022. doi: 10.2196/35497
21. Park C, Blevins KM, Paul AV, Long JS, Meyer LE, Anakwenze OA. Perioperative management in shoulder arthroplasty: a review of current practice. Orthop Clin North Am. Accepted.
22. Park C, Jones MM, Kaplan S, Koller FL, Wilder JM, Boulware B, McElroy LM. Inequities in access to organ transplant: a systematic review. Int. J for Equity in Health. 2022. https://doi.org/10.1186/s12939-021-01616-x
23. Rethorn ZD, Cook CE, Park C, Somers T, Mummaneni PV, Chan AK, Pennicooke BH, Bisson EF, Asher AL, Buchholz AL, Bydon M, Ali MA, Coric D, Foley KT, Fu KM, Knightly JJ, Meyer S, Park P, Potts EA, Shaffrey CI, Shaffrey M, Than KD, Tumialan L, Turner JD, Upadhyaya CD, Wang MY, Gottfried ON. Social risk factors predicting outcomes of cervical myelopathy surgery. J Neurosurg Spine. 2022. doi: 10.3171/2021.12.SPINE21874
24. Wang TY, Park C, Zhang H, Rahimpour S, Murphy KR, Goodwin CR, Karikari IO, Than KD, Shaffrey CI, Foster N, Abd-El-Barr MM. Management of Acute Traumatic Spinal Cord Injury: A Review of the Literature. Front. Surg. 2021. doi: 10.3389/fsurg.2021.698736
25. Wang TY, Park C, Dalton T, Rajkumar D, McCray E, Owolo E, Than KD, Abd-El-Barr MM. Robotic navigation in spine surgery: Where are we now and where are we going? J Clin Neuro. 2021. doi: 10.1016/j.jocn.2021.10.034
26. Xia M, Kheterpal MK, Wong SC, Park C, Ratliff W, Carin L, Henao R. Malignancy Prediction and Lesion Identification from Clinical Dermatological Images. 2021. arXiv: 2104.02652.
27. Park C, Gottfried ON. Commentary: Preoperative Hemoglobin A1c > 8% is Associated with Poor Outcomes in Lumbar Spine Surgery: A Michigan Spine Surgery Improvement Collaborative Study. Neurosurgery. 2021. doi: 10.1093/neuros/nyab327
28. Park C, Cook CE, Garcia AN, Gottfried ON. Discharge Destination Influences Risks of Readmissions and Complication After Lumbar Spine Surgery in Severely Disabled Patients. Clin Neuro Neurosurg. 2021. https://doi.org/10.1016/j.clineuro.2021.106801
29. Park C, Crutcher C, Mehta VA, Wang TY, Than KD, Karikari IO, Goodwin CR, Abd-El-Barr MM. Robotic-Assisted Percutaneous Iliac Screw Fixation for Destructive Lumbosacral Metastatic Lesions: An Early Single-Institution Experience. Acta Neurochirurgica. 2021. doi: 10.1007/s00701-021-04894-0
30. Park C, Thompson EM. Response to Letter to the Editor: Post-Operative hydrocephalus in children with posterior fossa tumors. 2021. J Neurosurg Pediatr. doi: 10.3171/2021.9.PEDS21433
31. Park C, Liu B, Hodges SE, Harward SC, Gloria J, Zhang AR, Lee HJ, Thompson EM. Clinical and Radiographic Predictors of Permanent CSF Diversion Following Posterior Fossa Tumor Resection in Pediatric Patients. J Neursurg Pediatr. 2021. doi: 10.3171/2021.4.PEDS2188
32. Park C, Chen M, Kim T. Implication of Auditory Confound in Interpreting Somatosensory and Motor Responses in Low-Intensity Focused Transcranial Ultrasound Stimulation. J Neurophysiol. 2020. doi: 10.1152/jn.00701.2020
33. Bergin SM, Wang TY, Park C, Rajkumar S, Goodwin CR, Karikari IO, Abd-El-Bar MM, Shaffrey CI, Yarbrough CK, Than KD. Multi-institutional Analysis on Rate of Pseudoarthrosis Following Anterior Cervical Discectomy and Fusion Using Allograft Cellular Bone Matrix (Osteocel). Neurosurg Focus. 2021. doi: 10.3171/2021.3.FOCUS2166
34. De la Garza Ramos R, Park C, McCracy E, Price M, Wang TY, Dalton T, Erickson MM, Foster N, Than KD, Abd-El-Barr MM, Karikari IO, Shaffrey CI, Yassari R, Goodwin CR. Effect of Interhospital Transfer Status on Patient Outcomes in Individuals with Spinal Metastasis Disease in the United States. Neurosurgical Focus. 2021. Doi: 10.3171/2021.2.FOCUS201085
35. Kim T, Park C, Chhatbar PY, Feld J, Mac Grory B, Chen M, Jiang X, Feng W. Effect of Low Intensity Transcranial Ultrasound Stimulation on Neuromodulation in Animals and Humans: An Updated Systematic Review and Narrative Synthesis. Front Neurosci. 2020. doi: 10.3389/fnins.2021.620863
36. Humayun LL, Smith C, Li W, Zhang YS, Park C, Feng W, Yao J. SARS-CoV-2 Vascular Injury: Emerging Technology for Imaging and Tissue Models. Microphysiol Syst. 2021. doi: 10.21037/mps-20-6
37. Samoylova ML, Wegermann K, Shaw BI, Kesseli S, Au S, Park C, Halpern SE, Sanoff S, Barbas AS, Patel YA, McElroy L. The Impact of the 2017 Kidnney Allocation Policy Change on Simultaneous Liver Kidney Utilization and Outcomes. Liver Transplantation. 2020. doi: 10.1002/lt.26053
38. Cook CE, Garcia AN, Park C, Gottfried ON. True Differences in Poor Outcome Risks Between Revision and Primary Lumbar Spine Surgeries. HSSJ. 2020. https://doi.org/10.1177/1556331621995136
39. Park C, Waguia Kouam R, Foster NA, Abd-El-Barr MM, Goodwin CR, Karikari IO. “The Eye Sees Only What the Mind is Prepared to Comprehend”: Unrecognized Findings on Intraoperative Computed Tomography During Spine Surgery. Clin Imag. 2020. 10.1016/j.clinimag.2020.11.034
40. Park C, Charalambous LT, Yang Z, Adil SM, Hodges SE, Lee HJ, Verbick LZ, McCabe A, Lad SP. Inpatient Mortality and Healthcare Resource Utilization of Intracerebral Hemorrhage Complications in the US. J Neurosurg. 2020. doi: 10.3171/2020.8.JNS201839
41. Park C, Garcia AN, Cook C, Gottfried ON. Effect of Change in Preoperative Depression/Anxiety on Patient Outcomes Following Lumbar Spine Surgery. Clin Neurol Neurosurg. 2020. doi: 10.1016/j.clineuro.2020.106312
42. Park C, Zakare-Fagbamila RT, Dickson W, Amin K, Giuliano J, Jimenez-Contreras F, Gottfried ON. Institutional Review of Predictors of In-Hospital and 30-Day Discharge Mortality in Neurosurgical Patients. Clin Neurol Neurosurg. 2020. doi: 10.1016/j.clineuro.2020.106231
43. Park C, Garcia AN, Cook CE, Shaffrey CI, Gottfried ON. Long-Term Impact of Obesity on Patient-Reported Outcomes and Patient Satisfaction After Lumbar Spine Surgery: An Observational Study. J Neurosurg Spine. 2020. doi: 10.3171/2020.6.SPINE20592
44. Park C, Howell EP, Mehta VA, Ramirez L, Price MJ, Kirkpatrick JP, Abd-El-Barr M, Karikari IO, Torok J, Floyd S, Goodwin CP. Patient Outcomes and Tumor Control in Single-Fraction versus Hypofractionated Stereotactic Body Radiation Therapy for Spinal Metastases. J Neurosurg Spine. 2020. doi: 10.3171/2020.6.SPINE20349
45. Park C, Zakare-Fagbamila RT, Dickson W, Garcia AN, Gottfried ON. The Limited Influence of Neurosurgeons’ Behavior on Inpatient Satisfaction: A Retrospective Multi-Hospital Analysis. J Neurosurg. 2020. 10.3171/2020.5.JNS20923
46. Park C, Patel YA, Suhocki P, Dorsey C, Kapila N, Tang L, Gilner J. High-Risk Third Trimester Pregnancy with Decompensated Cirrhosis Safely Delivered Following Emergent Preoperative Interventional Radiology for Mitigation of Variceal Bleeding. Clin Imag. 2020. 10.1016/j.clinimag.2020.06.032
47. Zakare-Fagbamila, RT, Park C, Dickson W, Cheng TZ, Gottfried ON. The true penalty of the waiting room: the role of wait time in patient satisfaction in a busy spine practice. J Neurosurg Spine. 2020. 1-11. doi: 10.3171/2019.12.SPINE191257
48. Spears CA, Hodges SE, Kiyani M, Yang Z, Edwards RM, Musick A, Park C, Parente B, Lee HJ, Lad SP. Healthcare Resource Utilization and Management of Chronic, Refractory Low Back Pain in the United States. Spine. 2020. doi:10.1097/BRS.0000000000003572
49. Park C, Steele J, Adams S. Bone Marrow Stimulation plus Bone Marrow Aspirate Concentrate versus Bone Marrow Stimulation Alone in the Treatment of Osteochondral Lesions of the Talus: A Prospective Study. Duke Orthopedic Journal. 2019. 9(1):1-5. doi: 10.4103/DORJ.DORJ_5_19
50. Sankey EW, Park C, Howell EP, Pennington Z, Abd-El-Barr M, Karikari IO, Schaffrey CI, Gokaslan ZL, Sciubba D, Goodwin CR. Importance of Spinal Alignment in Primary and Metastatic Spine Tumors. World Neurosurgery. 2019. 132:118-128. doi:10.1016/j.wneu.2019.08.161
51. Park C, Schappe T, Peskoe S, Mohottige D, Chan N, Bhavsar NA, Boulware LE, Pendergast J, Kirk AD, McElroy LM. A comparison of composite indices of social deprivation in transplant populations. Am J Transplant. doi: 10.1016/j.ajt.2022.11.018
52. Wong SC, Ratliff W, Xia M, Park C, Sendak M, Balu S, Henao R, Carin L, Kheterpal MK. Use of Convolutional Neural Networks in Skin Lesion Analysis Using Real World Image and Non-Image Data. Frontier Dermatology.
53. Hu S, Park C, Grimm LJ, Baker JA, Taylor-Cho MW, Mazurowski MA. Fully Automated Deep Learning Method for Fibroglandular Tissue Segmentation in Breast MRI. BMC Medical Informatics and Decision Making.
54. Gu H, Li K, Colglazier RJ, Yang J, O’Donnell J, Jiranek WA, Mather RC, Lebhar M, French RJ, Said N, Zhang J, Park C, Mazurowski MA. Automated grading of radiographic knee osteoarthritis severity combing with joint space narrowing. IEEE Journal of Biomedical and health informatics.
55. Samoylova ML, Kesseli SJ, Park C, Yerxa J, Horslen S, Jafri SM, Mavis Al, Schiano T, Summers B, Barbas AS, Sudan DL, Segovia MC. Three Decades of Intestinal and Multivisceral Transplantation in the United States. Clin Transplant.
56. Assaad S, Dov D, Park C, Davis R, Kovalsky S, Lee WT, Kahmke RR, Rocke DJ, Cohen J, Weiss-Meilik A, Henao R, Carin L, Range D. Comparing thyroid cancer molecular tests with a whole slide image-based deep learning algorithm. Thyroid.
57. Park C, Zakare-Fagbamila R, Gottfried ON. “Chapter 310: Bone Metabolism and Osteoporosis.” Youmans & Winn Neurological Surgery, 8e. Philadelphia, PA: Elsevier.
58. Park C, Weiss M, Feng W. Botulinum Toxin for Post-Stroke Limb Spasticity. Ischemic Stroke Therapeutics. Switzerland: Springer.
59. Park C, Agarwal N, Berven SH. Spinopelvic Alignment: Importance in Spinal Pathologies and Realignment Strategies. Neurosurgery Clinics Deformity Update.
60. Park C, Shabani S, Agarwal N, Lee T, Mummaneni PV. Robotic-Assisted Surgery and Navigation in Deformity Surgery. Neurosurgery Clinics Deformity Update.