Jason Scott Hauptman, MD, PhD

Portrait of Jason Hauptman, MD, PhD
Job Title
Associate Professor of Neurological Surgery

Dr. Jason S. Hauptman is an associate professor of neurological surgery and a board-certified pediatric neurosurgeon. He is a staff neurosurgeon at both Seattle Childrens Hospital and Harborview Medical Center. He dedicates a significant portion of his clinical practice to the surgical management of epilepsy, both in children (Seattle Children’s Hospital) and adults (Harborview Medical Center). For the surgical management of epilepsy, he focuses on the utilization of stereoelectroencephalography (sEEG) including using the ROSA Robotic System, stereotactic laser thermoablation (LITT), neuromodulation such as VNS and RNS, and open surgery such as lobectomy, hemispherectomy, and corpus callostomy. Dr. Hauptman also has a clinical interest in the surgery of tumors involving eloquent cortex, using techniques such as fMRI/rsfMRI planning and awake functional mapping. His research focuses on translation of novel therapeutics to the bedside, including targeted molecular therapies for epilepsy, as well as patient-oriented approaches to improve outcomes in epilepsy and pediatric neurosurgery.
Dr. Hauptman received his undergraduate degree from Muhlenberg College. He then received his M.D. from the University of Medicine and Dentistry of New Jersey (now called Rutgers Medical School). He went on to complete his neurological surgery residency at the University of California, Los Angeles under the leadership of Dr. Neil Martin. During this time he also completed a doctoral degree in neuroscience, studying the cellular neurophysiology of epilepsy in cortical dysplasia and tuberous sclerosis. He then went on to complete his pediatric neurosurgery fellowship at the Children's Hospital of Pittsburgh under the guidance of Dr. Ian Pollack. He holds a certificate in clinical trials from the University of Washington.

Clinical Interest

Clinical interests include brain tumors, epilepsy, vascular disorders (arteriovenous malformations, aneurysms, moyamoya disease), hydrocephalus, congenital brain and spine malformations, spine disorders including tethered cord syndrome/spinal cord lipomas and Chiari malformation.

Research Interests

Research interests include pediatric epilepsy surgery and pediatric brain tumors

Personal Interests

Spending time with my family, listening to music, cooking, spending time outdoors


Medical Education

Rutgers New Jersey Medical School


UCLA David Geffen School of Medicine, Los Angeles


Children's Hospital of Pittsburgh

  • Ivan Y, Hauptman J, Marin JR

    Abdominal Cerebrospinal Fluid Pseudocyst Diagnosed by Point-of-Care Ultrasound.
    27253360 Pediatric emergency care , 2016 June : 32(6)408-9
  • Kim W, Chivukula S, Hauptman J, Pouratian N

    Diffusion Tensor Imaging-Based Thalamic Segmentation in Deep Brain Stimulation for Chronic Pain Conditions.
    27537848 Stereotactic and functional neurosurgery , 2016 : 94(4)225-234 PMCID: PMC5083182
  • Gandhoke GS, Hauptman JS, Salvetti DJ, Weiner GM, Panigrahy A, Yilmaz S, Pollack IF

    Transosseous cerebrospinal fluid fistula 14 years after Chiari decompression: presentation and management.
    25978535 Journal of neurosurgery. Pediatrics , 2015 Aug. : 16(2)146-9
  • Hauptman JS, Dadour A, Oh T, Baca CB, Vickrey BG, Vassar S, Sankar R, Salamon N, Vinters HV, Mathern GW

    Time to pediatric epilepsy surgery is longer and developmental outcomes lower for government compared with private insurance.
    23615092 Neurosurgery , 2013 July : 73(1)152-7
  • Baca CB, Vickrey BG, Vassar S, Hauptman JS, Dadour A, Oh T, Salamon N, Vinters HV, Sankar R, Mathern GW

    Time to pediatric epilepsy surgery is related to disease severity and nonclinical factors.
    23468549 Neurology , 2013 Mar. 26 : 80(13)1231-9 PMCID: PMC3691779
  • Hauptman JS, Dadour A, Oh T, Baca CB, Vickrey BG, Vassar SD, Sankar R, Salamon N, Vinters HV, Mathern GW

    Sociodemographic changes over 25 years of pediatric epilepsy surgery at UCLA.
    23331214 Journal of neurosurgery. Pediatrics , 2013 Mar. : 11(3)250-5 PMCID: PMC3832187
  • Lall RR, Lall RR, Hauptman JS, Munoz C, Cybulski GR, Koski T, Ganju A, Fessler RG, Smith ZA

    Intraoperative neurophysiological monitoring in spine surgery: indications, efficacy, and role of the preoperative checklist.
    23116090 Neurosurgical focus , 2012 Nov. : 33(5)E10
  • Hauptman JS, Pedram K, Sison CA, Sankar R, Salamon N, Vinters HV, Mathern GW

    Pediatric epilepsy surgery: long-term 5-year seizure remission and medication use.
    22895408 Neurosurgery , 2012 Nov. : 71(5)985-93
  • Hauptman JS, Mathern GW

    Surgical treatment of epilepsy associated with cortical dysplasia: 2012 update.
    22946727 Epilepsia , 2012 Sept. : 53 Suppl 498-104
  • Hauptman JS, Salamon N, Mathern GW

    Neuroimaging in the definition and organization of the epilepsies: we're not there yet.
    22765501 Epilepsia , 2012 July : 53 Suppl 222-7 PMCID: PMC3397398
  • Hauptman JS, Barkhoudarian G, Safaee M, Gorgulho A, Tenn S, Agazaryan N, Selch M, De Salles AA

    Challenges in linear accelerator radiotherapy for chordomas and chondrosarcomas of the skull base: focus on complications.
    22137019 International journal of radiation oncology, biology, physics , 2012 June 1 : 83(2)542-51
  • Hauptman JS, Mathern GW

    Vagal nerve stimulation for pharmacoresistant epilepsy in children.
    23230532 Surgical neurology international , 2012 : 3(Suppl 4)S269-74 PMCID: PMC3514916
  • Everson R, Hauptman JS

    From the bench to the bedside: Brain-machine interfaces in spinal cord injury, the blood-brain barrier, and neurodegeneration, using the hippocampus to improve cognition, metabolism, and epilepsy, and understanding axonal death.
    23087824 Surgical neurology international , 2012 : 3108 PMCID: PMC3475876
  • Hauptman JS, Mathern GW

    Epilepsy neurosurgery in children.
    22939072 Handbook of clinical neurology , 2012 : 108881-95
  • Chow DS, Hauptman JS, Wong TT, Gonzalez NR, Martin NA, Lignelli AA, Itagaki MW

    Changes in stroke research productivity: A global perspective.
    22439118 Surgical neurology international , 2012 : 327 PMCID: PMC3307235
  • Cepeda C, André VM, Hauptman JS, Yamazaki I, Huynh MN, Chang JW, Chen JY, Fisher RS, Vinters HV, Levine MS, Mathern GW

    Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex.
    21889982 Neurobiology of disease , 2012 Jan. : 45(1)310-21 PMCID: PMC3225687
  • Hauptman JS, Chow DS, Martin NA, Itagaki MW

    Research productivity in neurosurgery: trends in globalization, scientific focus, and funding.
    21962030 Journal of neurosurgery , 2011 Dec. : 115(6)1262-72
  • Hauptman JS, Moftakhar P, Dadour A, Malkasian D, Martin NA

    Advances in the biology of cerebral cavernous malformations.
    20975979 Surgical neurology international , 2010 Oct. 11 : 163 PMCID: PMC2958334
  • Cepeda C, André VM, Yamazaki I, Hauptman JS, Chen JY, Vinters HV, Mathern GW, Levine MS

    Comparative study of cellular and synaptic abnormalities in brain tissue samples from pediatric tuberous sclerosis complex and cortical dysplasia type II.
    20618424 Epilepsia , 2010 July : 51 Suppl 3160-5 PMCID: PMC2909023
  • He W, Hauptman J, Pasupuleti L, Setton A, Farrow MG, Kasper L, Karimi R, Gandhi CD, Catrambone JE, Prestigiacomo CJ

    True posterior communicating artery aneurysms: are they more prone to rupture? A biomorphometric analysis.
    19747044 Journal of neurosurgery , 2010 Mar. : 112(3)611-5
  • Lerner JT, Salamon N, Hauptman JS, Velasco TR, Hemb M, Wu JY, Sankar R, Donald Shields W, Engel J Jr, Fried I, Cepeda C, Andre VM, Levine MS, Miyata H, Yong WH, Vinters HV, Mathern GW

    Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience.
    19175385 Epilepsia , 2009 June : 50(6)1310-35
  • Moftakhar P, Hauptman JS, Malkasian D, Martin NA

    Cerebral arteriovenous malformations. Part 2: physiology.
    19408989 Neurosurgical focus , 2009 May : 26(5)E11
  • Moftakhar P, Hauptman JS, Malkasian D, Martin NA

    Cerebral arteriovenous malformations. Part 1: cellular and molecular biology.
    19408988 Neurosurgical focus , 2009 May : 26(5)E10
  • Hauptman JS, DeSalles AA, Espinoza R, Sedrak M, Ishida W

    Potential surgical targets for deep brain stimulation in treatment-resistant depression.
    18590380 Neurosurgical focus , 2008 : 25(1)E3